Human ochratoxicosis and nephropathy in Egypt: A preliminary study
| Autor: | EW Wafa, RS Yahya, MA Sobh, I Eraky, M El-Baz, HAM El-Gayar, AM Betbeder, EE Creppy |
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| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: | |
| Zdroj: | African Journal of Nephrology, Vol 2, Iss 1, Pp 43-48 (1998) |
| Druh dokumentu: | article |
| ISSN: | 2306-8205 2518-4601 |
| DOI: | 10.21804/2-1-862 |
| Popis: | This preliminary study was designed todelineate the extent of the problem of ochratoxicosis and its relation to renal diseases mounting to end stage renal disease (ESRD) or urothelial tumors in Egypt. It comprised 71 patient with renal diseases of different presentations. They were divided into five groups: (group I - no.=11) patients with (ESRD)under conservative treatment, (group 2 - no.=15)ESRD on regular hemodialysis, (group3 - no.= 15)renal allograft recipients, (group 4 - no.=15) patients with nephrotic syndrome and (group 5 - no.=15)patients with urothelial tumors. In addition, two control groups were included; potential related donors for renal transplantation (group 6 - no.=15)and healthy controls with negative family history of renal disease (group 7 - no.=25).All groups were subjected to clinical, laboratory, radiological and histopathological evaluation of renal status together with determination of ochratoxin A level in blood, urine and in biopsy specimens of patients with urothelial tumors. High ochratoxin blood levels were found in all patients with ESRD (groups 1 & 2) (p |
| Databáze: | Directory of Open Access Journals |
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