The role of beluntas (pluchea indica less.) leaf extract in preventing the occurrence of fibroblasts hyperproliferation: An in vitro preliminary study
| Autor: | Sakti Charlia Maharani, Indah Julianto, Suci Widhiati |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Dermatology Reports, Vol 11, Iss 1s (2019) |
| Druh dokumentu: | article |
| ISSN: | 2036-7392 2036-7406 |
| DOI: | 10.4081/dr.2019.8019 |
| Popis: | Beluntas (Pluchea indica Less.) is a herbal plant which contains variety of benefits. Quercetin, one of flavonoid, is the most bioactive agent in beluntas leaf. Collagen inhibition by quercetin may modulate extracellular matrix deposition and inhibit the formation of hypertrophic scar. This was an in vitro study with senescent fibroblasts to determine the role of beluntas leaf extract in preventing the occurence of fibroblasts hyperproliferations. There were 4 groups were stained by anti-collagen I antibodies and secondary antibody. Flowcytometry analysis was done to measure the fibroblasts density. Anova test was performed with a value of p=0.000 (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|