Associations of Anaplasma phagocytophilum Bacteria Variants in Ixodes scapularis Ticks and Humans, New York, USA
| Autor: | Melissa Prusinski, Collin O’Connor, Alexis Russell, Jamie Sommer, Jennifer White, Lauren Rose, Richard Falco, John Kokas, Vanessa Vinci, Wayne Gall, Keith Tober, Jamie Haight, JoAnne Oliver, Lisa Meehan, Lee Ann Sporn, Dustin Brisson, P. Bryon Backenson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Emerging Infectious Diseases, Vol 29, Iss 3, Pp 540-550 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1080-6040 1080-6059 |
| DOI: | 10.3201/eid2903.220320 |
| Popis: | Anaplasmosis, caused by the tickborne bacterium Anaplasma phagocytophilum, is an emerging public health threat in the United States. In the northeastern United States, the blacklegged tick (Ixodes scapularis) transmits the human pathogenic genetic variant of A. phagocytophilum (Ap-ha) and a nonpathogenic variant (Ap-V1). New York has recently experienced a rapid and geographically focused increase in cases of anaplasmosis. We analyzed A. phagocytophilum–infected I. scapularis ticks collected across New York during 2008–2020 to differentiate between variants and calculate an entomological risk index (ERI) for each. Ap-ha ERI varied between regions and increased in all regions during the final years of the study. Space-time scan analyses detected expanding clusters of Ap-ha located within documented anaplasmosis hotspots. Ap-ha ERI was more positively correlated with anaplasmosis incidence than non-genotyped A. phagocytophilum ERI. Our findings help elucidate the relationship between the spatial ecology of A. phagocytophilum variants and anaplasmosis. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|