Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum
| Autor: | Prabhas Prasun Giri, Swapan Roy, Sukanta Bhattyacharya, Priyankar Pal, Sandipan Dhar |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Indian Journal of Dermatology, Vol 56, Iss 6, Pp 763-765 (2011) |
| Druh dokumentu: | article |
| ISSN: | 0019-5154 1998-3611 |
| DOI: | 10.4103/0019-5154.91850 |
| Popis: | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome reflects a serious hypersensitivity reaction to drugs, and is characterized by skin rash, fever, lymph node enlargement, and internal organ involvement. So far, numerous drugs such as sulfonamides, phenobarbital, sulfasalazine, carbamazepine, and phenytoin have been reported to cause DRESS syndrome. We report a case of a 10-year-old girl who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (hepatitis and pneumonitis) after taking phenobarbital for seizures, with subsequent development of sepsis, acute respiratory distress syndrome (ARDS) and spontaneous air leak syndrome (pnemothorax and pneumomediastinum). She was put on steroids and various antibiotics and was ventilated, but ultimately succumbed to sepsis and pulmonary complications. |
| Databáze: | Directory of Open Access Journals |
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