Alzheimer’s Disease Detection via Multiscale Feature Modelling Using Improved Spatial Attention Guided Depth Separable CNN

Autor: Santosh Kumar Tripathy, Rudra Kalyan Nayak, Kartik Shankar Gadupa, Rajnish Dinesh Mishra, Ashok Kumar Patel, Santosh Kumar Satapathy, Akash Kumar Bhoi, Paolo Barsocchi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Computational Intelligence Systems, Vol 17, Iss 1, Pp 1-17 (2024)
Druh dokumentu: article
ISSN: 1875-6883
DOI: 10.1007/s44196-024-00502-y
Popis: Abstract Early detection of Alzheimer's disease (AD) is critical due to its rising prevalence. AI-aided AD diagnosis has grown for decades. Most of these systems use deep learning using CNN. However, a few concerns must be addressed to identify AD: a. there is a lack of attention paid to spatial features; b. there is a lack of scale-invariant feature modelling; and c. the convolutional spatial attention block (C-SAB) mechanism is available in the literature, but it exploits limited feature sets from its input features to obtain a spatial attention map, which needs to be enhanced. The suggested model addresses these issues in two ways: through a backbone of multilayers of depth-separable CNN. Firstly, we propose an improved spatial convolution attention block (I-SAB) to generate an enhanced spatial attention map for the multilayer features of the backbone. The I-SAB, a modified version of the C-SAB, generates a spatial attention map by combining multiple cues from input feature maps. Such a map is forwarded to a multilayer of depth-separable CNN for further feature extraction and employs a skip connection to produce an enhanced spatial attention map. Second, we combine multilayer spatial attention features to make scale-invariant spatial attention features that can fix scale issues in MRI images. We demonstrate extensive experimentation and ablation studies using two open-source datasets, OASIS and AD-Dataset. The recommended model outperforms existing best practices with 99.75% and 96.20% accuracy on OASIS and AD-Dataset. This paper also performed a domain adaptation test on the OASIS dataset, which obtained 83.25% accuracy.
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