| Autor: |
K.S. Sahana, Anitha S Prabhu, Prakash RM Saldanha |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 11, Iss , Pp 7-9 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2405-5794 |
| DOI: |
10.1016/j.jctube.2017.12.002 |
| Popis: |
Background: Diagnosis of Tuberculosis in children is challenging. Hereby we report a case series of 4 patients where Cartridge Based Nucleic Acid Amplification Test (CB NAAT) helped us in early diagnosis. Case characteristics: Case 1 was a 14-year old girl who was on anti-tuberculous therapy (ATT) for 2 months without any improvement; sputum CBNAAT detected multi-drug resistant tuberculosis (MDR-TB). Case 2 was a 9-year old boy with history and examination findings suggestive of meningitis; CB-NAAT of the cerebrospinal fluid (CSF) was positive. Case 3 was a 1-year old child having fever, cough of 1 month duration with Mantoux positive. CB-NAAT of gastric lavage was positive. Case 4 was a 3- month old child who presented with severe respiratory distress of 11 days duration. Chest x-ray showed miliary mottling; CB-NAAT of gastric lavage was positive. Conclusion: CB-NAAT testing was very useful in making an early and definitive diagnosis of tuberculosis, including MDR-TB. Keywords: CB-NAAT, Pediatric, Tuberculosis, GeneXpert |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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