Autor: |
Violeta I. Gallardo-Montejano, Chaofeng Yang, Lisa Hahner, John L. McAfee, Joshua A. Johnson, William L. Holland, Rodrigo Fernandez-Valdivia, Perry E. Bickel |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-021-23601-2 |
Popis: |
Perilipin 5 is a lipid droplet protein that interacts with PGC1α in the nucleus to regulate mitochondrial metabolism. Here the authors use genetically engineered mouse models to determine the physiologic role of Perilipin 5, and show that it regulates mitochondrial adaptations to cold, as well as systemic energy metabolism. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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