Acute effects of exercise on macro- and microvasculature in individuals with type 1 diabetes – a secondary outcome analysis

Autor: Adam Saloň, Karin Schmid-Zalaudek, Bianca Steuber, Alexander Müller, Othmar Moser, Suhaila Alnuaimi, Per Morten Fredriksen, Benedicta Ngwenchi Nkeh-Chungag, Nandu Goswami
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Endocrinology, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1664-2392
DOI: 10.3389/fendo.2024.1406930
Popis: BackgroundType 1 diabetes is a chronic autoimmune disease associated with insulin-producing beta cell destruction, declining insulin secretion, and elevated blood glucose. Physical activity improves glycaemic control and cardiovascular health. This study explores acute effects of maximal exhaustion induced by a cardiopulmonary exercise on macro- and microvascular parameters in type 1 diabetes.MethodologyTwenty-five participants with type 1 diabetes (14 males, 11 females), aged 41.4 ± 11.87 years, BMI 23.7 ± 3.08, completed a repeated-measure study. Measurements pre-, post-, 30- and 60-minutes post-exhaustion involved a maximal incremental cardio-pulmonary exercise test. Macro- and microvascular parameters were assessed using VICORDER® and retinal blood vessel image analysis. Repeated measures ANOVA in SPSS (Version 27.0) analysed data.ResultsPost-exercise, heart rate increased (p
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