Persistence of expiratory flow limitations between normoxia and hypoxia

Autor: Raberin Antoine, Giorgio Manferdelli, Forrest Schorderet, Nicolas Bourdillon, Grégoire P. Millet
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Current Issues in Sport Science, Vol 9, Iss 2 (2024)
Druh dokumentu: article
ISSN: 2414-6641
DOI: 10.36950/2024.2ciss066
Popis: Introduction Expiratory flow limitation (EFL) refers to the inability to generate higher airflow despite greater respiratory effort and is common in both men and women. In normoxic condition, EFL is contingent upon an imbalance between ventilatory demands and capacity. Since hypoxia is known to alter ventilatory drive and pattern, it may influence the development of EFL. Therefore, the aim of this study was to investigate the origin of EFL in hypoxia and its repeatability and persistence during exercise in hypoxia. Method Fifty-one healthy active individuals (27 men and 24 women) performed a lung function test and a maximal incremental exercise test on a cycle-ergometer in normoxia and hypoxia (inspired oxygen fraction = 0.14) on two separate visits. Ventilatory capacity, assessed using the slope ratio (SR), were evaluated from maximal flow volume curve analyses. Results During exercise in normoxia, 28 participants exhibited EFL (55%). Another set of 28 participants exhibited EFL in hypoxia but they were not all the same individuals as those in normoxia. In normoxia, both SR and maximum minute ventilation (V̇E) were higher in the EFL group than the non-EFL group (p = 0.029 and p
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