Preoperative risk assessment for postoperative pancreatic fistula (POPF): Image-based calculation of duct-to-parenchyma (D/P) ratio and an Alignment of Duct and Mucosa (ADAM) anastomosis may lead to a low POPF rate—results from 386 patients

Autor: Colin M. Krueger, Melanie Langheinrich, Esther A. Biesel, Lena Kundel, Karsten Krueger, Ulrich Adam, Hartwig Riediger
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Surgery, Vol 9 (2022)
Druh dokumentu: article
ISSN: 2296-875X
DOI: 10.3389/fsurg.2022.1039191
Popis: BackgroundPostoperative pancreatic fistula (POPF) is the most critical complication after pancreatoduodenectomy (PD). Preoperative identification of high-risk patients and optimal pancreatic reconstruction technique can be a way to reduce postoperative complications.MethodsA series of 386 patients underwent PD over a 10-year period (2009–2019). On routinely performed preoperative computed tomography (CT) images, the ventro-dorsal diameters of duct (D) and parenchyma (P) were measured in the cutting plane at the superior mesenteric vein. Then, the ratio of both values was calculated (D/P ratio) Double-layer pancreatojejunostomy with alignment of duct and mucosa (ADAM) by two monofilament threads (MFT) was performed in 359 patients and pancreatogastrostomy (PG) in 27 patients. The incidence of POPF was diagnosed according to the International Study Group for Pancreatic Fistula criteria.ResultsThe overall rate of POPF was 21% (n = 80), and the rate of clinically relevant type B/C fistulas 6.5% (n = 25). A D/P ratio of 0.2), type B/C fistula occurred only in 2%, and in high-risk patients (D/P ratio
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