| Autor: |
XUE Yu, JIA Zhenyan, DU Yunsai, GONG Qian, DU Wenhua, GAO Guanqi |
| Jazyk: |
čínština |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
精准医学杂志, Vol 38, Iss 6, Pp 490-493 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2096-529X |
| DOI: |
10.13362/j.jpmed.202306005 |
| Popis: |
Objective To investigate the changes in serum thyrotropin receptor antibody (TRAb), thyroid stimulating antibody (TSAb), and thyroid-stimulating blocking antibody (TSBAb) and their significance in patients with Hashimoto’s thyroiditis with hypothyroidism (HT hypothyroidism). Methods A total of 133 patients with HT hypothyroidism (HT hypothyroidism group) and 125 healthy subjects (control group) were enrolled and their clinical data were collected. The serum levels of free triiodothyronine (FT3), free thyroxine (FT4), thyrotropin (TSH), and TRAb were measured and compared between the two groups. TSAb and TSBAb were also compared across the patients who were positive for TRAb (group B), who were negative for TRAb (group C), and the healthy subjects who were negative for TRAb (group A). A Pearson correlation analysis was used to examine the relationships between the serum levels of TSAb and TSBAb and the serum levels of FT3, FT4, TSH, and TRAb in patients with HT hypothyroidism. Results The serum TRAb level in the HT hypothyroidism group was significantly higher than that in the control group (Z=-5.434,P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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