Reducing transmission of methicillin-resistant Staphylococcus aureus in a surgical ward of a resource-limited hospital in Indonesia: an intervention study

Autor: Dewi Santosaningsih, Dewi Erikawati, Iffa A. Hakim, Sanarto Santoso, M. Hidayat, Ayu H. Suwenda, Vicky Puspitasari, Irhamni Irhamni, Kuntaman Kuntaman, Andreas L.E. van Arkel, Luke G. Terlouw, Neline Oudenes, Diana Willemse-Erix, Susan V. Snijders, Nicole S. Erler, Henri A. Verbrugh, Juliëtte A. Severin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Infection Prevention in Practice, Vol 1, Iss 3, Pp - (2019)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2019.100028
Popis: SUMMARY: Background: Methicillin-resistant Staphylococcus aureus (MRSA) is endemic in healthcare settings in Indonesia. Aim: To evaluate the effect of a bundle of preventive measures on the transmission and acquisition of MRSA in a surgical ward of a resource-limited hospital in Indonesia. Methods: The study consisted of a pre-intervention (7 months), intervention (2 months), and post-intervention phase (5 months) and included screening for MRSA among eligible patients, healthcare workers (HCWs), and the hospital environment. In the intervention phase, a bundle of preventive actions was introduced, comprising: a hand hygiene educational program, cohorting of MRSA-positive patients, decolonization therapy for all MRSA-positive patients and HCWs, and cleaning and disinfection of the ward's innate environment. Hand hygiene compliance was assessed throughout the study period. The primary outcome was the acquisition rate of MRSA among patients per 1,000 patient-days at risk. Clonality of MRSA isolates was determined by Raman spectroscopy and multilocus sequence typing. Findings: In total, 1,120 patients were included. Hand hygiene compliance rate rose from 15% pre-intervention to 65% post-intervention (P
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