| Autor: |
Thomas Zoller, Elirehema H. Mfinanga, Tresphory B. Zumba, Peter J. Asilia, Edwin M. Mutabazi, David Wimmersberger, Florian Kurth, Francis Mhimbira, Frederick Haraka, Klaus Reither |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2466 |
| DOI: |
10.1186/s12890-018-0577-9 |
| Popis: |
Abstract Background Chronic obstructive pulmonary disease is a global problem and available data from sub-Saharan Africa is very limited. Methods A cross-sectional facility-based pilot study among patients and visitors to an urban and a rural primary healthcare facility was conducted in coastal Tanzania. The primary outcome was the prevalence of chronic airflow obstruction. Results The final analysis included 598 participants with valid post-bronchodilator spirometry. Applying ATS/ERS spirometric criteria, chronic airflow obstruction was found in n = 24 (4%, CI95 2.7–5.9) participants and in n = 30 (5%, CI95 3.5–7.1) applying GOLD spirometric criteria. To analyse risk factors for chronic airflow obstruction including those not meeting ATS/ERS or GOLD criteria, FEF25–75 and FEV1% predicted was analysed in participants without evidence of pulmonary restriction among those exposed or not exposed to risk factors (n = 552). FEV1% predicted, but in particular FEF25–75 decreased with increasing symptom severity of shortness of breath as well as limitations in daily activities of participants. Cooking in general and cooking with biomass fuels vs. gas or electricity was associated with significantly lower FEF25–75, but not with lower FEV1% predicted. Participants having refrained from taking a job because of shortness of breath exhibited lower FEF25–75 (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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