Efavirenz Outperforms Boosted Atazanavir among Treatment-Naive HIV-1-Infected Persons in Routine Clinical Care

Autor: Toshibumi Taniguchi MD, Jessica R. Grubb MD, Diana Nurutdinova MD, Nur F. Önen MD, Enbal Shacham PhD, Michael Donovan BS, Edgar Turner Overton MD
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Journal of the International Association of Providers of AIDS Care, Vol 12 (2013)
Druh dokumentu: article
ISSN: 2325-9574
2325-9582
15451097
DOI: 10.1177/1545109712467057
Popis: Background: Effectiveness of antiretroviral therapy (ART) in a routine clinical care may result different from the clinical trials. We assessed the virologic outcomes in treatment-naive persons who received either efavirenz (EFV) or atazanavir/ritonavir (ATV/r) with a backbone of tenofovir/emtricitabine (TDF/FTC) as their combination ART (cART). Methods: This was a retrospective cohort study conducted at the Washington University HIV Outpatient Clinic from January 2004 to June 2009. Predictors of virologic suppression (HIV RNA level
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