Rapid, efficient and solvent free microwave mediated synthesis of aldo- and ketonitrones

Autor: Loredana Maiuolo, Antonio De Nino, Pedro Merino, Beatrice Russo, Gaetano Stabile, Monica Nardi, Napoleone D’Agostino, Tatiana Bernardi
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Arabian Journal of Chemistry, Vol 9, Iss 1, Pp 25-31 (2016)
Druh dokumentu: article
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2015.01.015
Popis: A library of C-alkyl and C-aryl nitrones has been obtained by direct condensation of primary N-substituted hydroxylamine hydrochlorides with various aldehydes and ketones without catalysts or base. The synthetic procedure, performed under MW irradiation in the absence of solvent, does not require the presence of a base, is fast, clean, high-yielding and characterized by simple work-up.
Databáze: Directory of Open Access Journals