Clinical Characteristics of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Asthma-chronic Obstructive Pulmonary Disease Overlap Patients with Different Low Attenuation Area Grades

Autor: GAO Sijie, CHEN Zelin, WU Siyu, WANG Zheng, MENG Aihong
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Zhongguo quanke yixue, Vol 27, Iss 12, Pp 1468-1474 (2024)
Druh dokumentu: article
ISSN: 1007-9572
DOI: 10.12114/j.issn.1007-9572.2023.0373
Popis: Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease. Asthma-COPD overlap (ACO) has clinical features both related to asthma and COPD. Some patients are unable to cooperate with pulmonary function tests, so it is difficult to determine the degree of airflow limitation. Objective To compare the clinical characteristics of different low attenuation area (LAA) grades in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and asthma-chronic obstructive pulmonary disease overlap (ACO), and analyze the correlation between forced expiratory volume in 1 second as a percentage of predicted value (FEV1%pred) and LAA grades, so as to provide a reference index for patients who are unable to receive pulmonary function tests. Methods The clinical data of AECOPD and ACO patients hospitalized in the Department of Pulmonary and Critical Care Medicine of the Second Hospital of Hebei Medical University from March 2020 to May 2022 were collected. The participants were divided into the four groups including the emphysema AECOPD group (150 cases), bronchitis AECOPD group (84 cases), emphysema ACO group (47 cases) and bronchitis ACO group (59 cases) according to the LAA grade, LAA≥2 as emphysema groups, LAA
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