Association between Osteoporosis and Skeletal Muscle Mass in Men

Autor: Masaya Mizutani, Yawara Eguchi, Toru Toyoguchi, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Satoshi Maki, Junichi Nakamura, Shigeo Hagiwara, Yasuchika Aoki, Masahiro Inoue, Masao Koda, Hiroshi Takahashi, Tsutomu Akazawa, Seiji Ohtori
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Asian Spine Journal, Vol 18, Iss 1, Pp 73-78 (2024)
Druh dokumentu: article
ISSN: 1976-1902
1976-7846
DOI: 10.31616/asj.2023.0165
Popis: Study Design Cross-sectional study. Purpose This cross-sectional study aimed to investigate the risk factors for osteoporosis in men by assessing bone mineral density (BMD), skeletal muscle mass, body fat mass, grip strength, and advanced glycation end products (AGEs). Overview of Literature Fewer studies have reported the correlation between BMD and skeletal muscle mass in women. Moreover, a few studies have examined the relationship between osteoporosis and skeletal muscle mass. Methods This study included 99 men (mean age, 74.9 years; range, 28–93 years) who visited Qiball Clinic for BMD and body composition examinations. The osteoporosis group consisted of 24 patients (mean age, 72.5 years; range, 44–92 years), and the control group consisted of 75 individuals (mean age, 74.9 years; range, 28–93 years). Whole-body skeletal muscle mass was measured using a bioelectrical impedance analyzer. BMD was measured by dual X-ray absorptiometry. Skin autofluorescence (SAF), a marker of dermal AGE accumulation, was measured using a spectroscope. Osteoporosis was defined as a bone density T score of −2.5 or less. Physical findings, skeletal muscle mass, BMD, grip strength, and SAF were compared between the osteoporosis and control groups. Results The osteoporosis group had significantly lower trunk muscle mass (23.1 kg vs. 24.9 kg), lower leg muscle mass (14.4 kg vs. 13.0 kg), and skeletal mass index (7.1 kg/m2 vs. 6.7 kg/m2) than the control group (all p
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