Immunobiological Characteristics of Cholera Toxin B-Subunit

Autor:	S. N. Klyueva, T. N. Shchukovskaya, T. P. Shmel’Kova, A. L. Kravtsov, S. A. Bugorkova, N. I. Smirnova, O. A. Volokh, T. L. Zakharova, N. I. Belyakova, S. A. Eremin, A. K. Nikiforov
Jazyk:	ruština
Rok vydání:	2012
Předmět:	в-субъединица холерного токсина токсичность протективность апоптоз антитоксические антитела cholera toxin b-subunit toxicity protective ability apoptosis anti-toxic antibodies Infectious and parasitic diseases RC109-216
Zdroj:	Проблемы особо опасных инфекций, Vol 0, Iss 3(113), Pp 67-70 (2012)
Druh dokumentu:	article
ISSN:	0370-1069 2658-719X
DOI:	10.21055/0370-1069-2012-3-67-70
Popis:	Carried out was immunobiological evaluation of cholera toxin B subunit preparations obtained using different experimental and production methods. It was demonstrated that B subunit preparations were non-toxic for biomodels and did not cause significant pathological alterations in their organs and tissues. They also did not alter the condition of immunocompetent cells at different stages of their cycle, and promote anti-toxic antibodies production. Thus, B subunit preparations under study can be considered as promising components of cholera vaccine.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/41d5c63be45a4ac8b06c6aa4bdf53ead Zobrazit plný text záznamu View record in DOAJ