Exercise modifies lipid and glucose metabolism alterations induced by sleep deprivation in mice

Autor: Bruna Rafaele Diogenes da Silva, Paulo Iury Gomes Nunes, Flavia Almeida Santos, Pedro Felipe Carvalhedo de Bruin, Veralice Meireles Sales de Bruin
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Sleep Science, Vol 15, Iss 03, Pp 347-350 (2022)
Druh dokumentu: article
ISSN: 1984-0659
1984-0063
DOI: 10.5935/1984-0063.20220061
Popis: Insufficient sleep compromises lipid/glucose homeostasis. In opposition, exercise increases energy expenditure and has positive effects on glucose and fatty acid metabolism. Presently, it is hypothesized that exercise ameliorates metabolic dysfunction associated with sleep deprivation (SD). The effects of exercise (EX), SD and EX before SD. (EX+SD) on lipid and glucose metabolism were evaluated. Swiss mice were assigned to 4 groups (N=12, each) control, exercise (EX, 8 weeks, 1-hour of treadmill/9cm/s, 5x/week, from noon to 1:00 p.m.), SD (SD-72h, multiple platforms method), and exercise before SD (EX+SD). Exercise increased blood glucose, lactate and triglycerides (p
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