Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits

Autor: Bingxin Zhao, Yue Shan, Yue Yang, Zhaolong Yu, Tengfei Li, Xifeng Wang, Tianyou Luo, Ziliang Zhu, Patrick Sullivan, Hongyu Zhao, Yun Li, Hongtu Zhu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-23130-y
Popis: Brain structural traits are highly heritable and have been linked to disease. Here the authors have used gene expression data to perform a transcriptome-wide association study on 211 brain structural traits, discovering 273 associated genes.
Databáze: Directory of Open Access Journals