An Arabidopsis mutant line lacking the mitochondrial calcium transport regulator MICU shows an altered metabolite profile

Autor:	Emilia R. Gutiérrez-Mireles, José Carlos Páez-Franco, Raúl Rodríguez-Ruíz, Juan Manuel Germán-Acacio, M. Casandra López-Aquino, Manuel Gutiérrez-Aguilar
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	mitochondrial calcium uniporter arabidopsis thaliana plant metabolism Plant ecology QK900-989 Biology (General) QH301-705.5
Zdroj:	Plant Signaling & Behavior, Vol 18, Iss 1 (2023)
Druh dokumentu:	article
ISSN:	1559-2316 1559-2324 15592324
DOI:	10.1080/15592324.2023.2271799
Popis:	Plant metabolism is constantly changing and requires input signals for efficient regulation. The mitochondrial calcium uniporter (MCU) couples organellar and cytoplasmic calcium oscillations leading to oxidative metabolism regulation in a vast array of species. In Arabidopsis thaliana, genetic deletion of AtMICU leads to altered mitochondrial calcium handling and ultrastructure. Here we aimed to further assess the consequences upon genetic deletion of AtMICU. Our results confirm that AtMICU safeguards intracellular calcium transport associated with carbohydrate, amino acid, and phytol metabolism modifications. The implications of such alterations are discussed.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/41b9fffdc70c4541b298d9864535e163 Zobrazit plný text záznamu View record in DOAJ