An insight into osteoarthritis susceptibility: Integration of immunological and genetic background
| Autor: | Debora Stefik, Vladimir Vranic, Nemanja Ivkovic, Dzihan Abazovic, Dusan Maric, Danilo Vojvodic, Gordana Supic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Biomolecules & Biomedicine, Vol 21, Iss 2 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2831-0896 2831-090X |
| DOI: | 10.17305/bjbms.2020.4735 |
| Popis: | Osteoarthritis (OA) is a progressive degenerative disease that affects all synovial joints, causing the disability of the main locomotor diarthrodial joints. OA pathogenesis is caused by a complex interplay between a number of genetic and environmental risk factors, involved in the early onset and progression of this chronic inflammatory joint disease. Uncovering the underlying immunological and genetic mechanisms will enable an insight into OA pathophysiology and lead to novel and integrative approaches in the treatment of OA patients, together with a reduction of the disease risk, or a delay of its onset in susceptible patients. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|