Validation of prognosis-based in vitro fertilization grant selection criteria

Autor: Jennifer B. Bakkensen, M.D., Elise Heisler, M.D., Katherine Bolten, M.D., Bahar Yilmaz, M.D., Jill Smiley, M.PH., Jennifer E. Hirshfeld-Cytron, M.D., Eve C. Feinberg, M.D.
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: F&S Reports, Vol 4, Iss 3, Pp 286-291 (2023)
Druh dokumentu: article
ISSN: 2666-3341
DOI: 10.1016/j.xfre.2023.06.006
Popis: Objective: To validate a prognosis-based scoring system for in vitro fertilization (IVF) grant allocation. Design: Retrospective cohort study. Setting: A 501(c)(3) nonprofit foundation that awards donated IVF cycles and grants to those with demonstrated financial need. In contrast to lottery-based or subjective allocation systems, applications are scored according to medical prognostic criteria in addition to personal characteristics. Patients: Grant recipients from 2015 to 2019. Interventions: None. Main outcome measures: Live birth rate (LBR) and cumulative LBR (CLBR) among grant recipients were compared with 2019 Society for Assisted Reproductive Technology (SART) national averages. Results: A total of 435 applications were reviewed, with 59 grants awarded for 51 autologous IVF cycles, 6 donor oocyte cycles, and 2 gestational carrier cycles, resulting in 39 live births after initial embryo transfer (LBR 61.9%) and 43 CLBRs (CLBR 72.9%). Among autologous cycles, the mean (±SD=3.9 years) age was 31.8 years, and LBR and CLBR were 62.8% and 68.6% vs. 28.2% and 37.1% among all autologous SART cycles, respectively. A subanalysis of grant recipients aged
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