Cutaneous Radiation-Associated Angiosarcoma After Cervical Cancer Treatment: A Case Report

Autor: Cong-Cong Xu, Wei Zhang, Hao Chen
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Dermatology and Venerology, Vol 4, Iss 4, Pp 263-265 (2021)
Druh dokumentu: article
ISSN: 2096-5540
2641-8746
00000000
DOI: 10.1097/JD9.0000000000000145
Popis: Abstract. Introduction:. Cutaneous radiation-associated (cRAA) angiosarcoma is a rare malignant neoplasm derived from vascular endothelial cells, but a relatively commonly recognized complication of radiation therapy. Here, we present a patient with cRAA, who undergone radiochemotherapy for cervical cancer 11 years ago. Case presentation:. A 48-year-old woman presented with a 6-month history of painless purple skin plaques and nodules on her lower abdomen and right thigh. The patient had undergone radiochemotherapy for cervical cancer 11 years ago. A skin biopsy showed a diffuse proliferation of irregular anastomosing dilated vascular structures with atypical endothelial cells. She was diagnosed as cRAA according to clinical and histological manifestations. Discussion:. cRAA is a rare malignant neoplasm but it is a complication of radiation therapy. The incidence of cRAA has increased in recent years. Clinical and pathological manifestations are highly varied. Radical resection is the preferred treatment. Conclusion:. Patients with suspicious violaceous lesions should undergo biopsy. Clinical suspicion and pathological examination are of the utmost importance for cRAA.
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