Juvenile Myelomonocytic Leukemia in a Premature Neonate Mimicking Neonatal Sepsis

Autor: Ming-Luen Lee, Hsiu-Ju Yen, Shu-Jen Chen, Giun-Yi Hung, Pei-Chen Tsao, Wen-Jue Soong
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Pediatrics and Neonatology, Vol 57, Iss 2, Pp 149-152 (2016)
Druh dokumentu: article
ISSN: 1875-9572
DOI: 10.1016/j.pedneo.2013.06.009
Popis: Juvenile myelomonocytic leukemia (JMML) is a rare hematologic malignancy in children. Its presentations include anemia, thrombocytopenia, monocytosis, skin rash, marked hepatomegaly, and/or splenomegaly. Fever and respiratory involvement are common. Here, we report a case of a premature neonate with initial symptoms of respiratory distress. She gradually developed clinical manifestations of JMML that mimicked neonatal sepsis. Three weeks after birth, JMML was diagnosed. This is the first reported case of JMML presenting in a premature infant in Taiwan.
Databáze: Directory of Open Access Journals