Brachial and central hypertension in relation to coronary stenosis in patients with coronary angiography

Autor: Yu Chen, Ming‐Xuan Li, Ying Wang, Xian Jin, Liang Liu, Zhen‐Fa Zhou, Feng‐Hua Ding, Rui‐Yan Zhang, Yan Li, Cheng‐Xing Shen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Journal of Clinical Hypertension, Vol 25, Iss 7, Pp 610-617 (2023)
Druh dokumentu: article
ISSN: 1751-7176
1524-6175
DOI: 10.1111/jch.14691
Popis: Abstract The clinical significance of central beyond brachial blood pressure (BP) remains unclear. In patients who underwent coronary angiography, the authors explored whether elevated central BP would be associated with coronary arterial disease (CAD) irrespective of the status of brachial hypertension. From March 2021 to April 2022, 335 patients (mean age 64.9 years, 69.9% men) hospitalized for suspected CAD or unstable angina were screened in an ongoing trial. CAD was defined if a coronary stenosis of ≥50%. According to the presence of brachial (non‐invasive cuff systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg) and central (invasive systolic BP ≥130 mmHg) hypertension, patients were cross‐classified as isolated brachial hypertension (n = 23), isolated central hypertension (n = 93), and concordant normotension (n = 100) or hypertension (n = 119). In continuous analyses, both brachial and central systolic BPs were significantly related to CAD with similar standardized odds ratios (OR, 1.47 and 1.45, p
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