Chemical Constituents and Biological Activities of Bruguiera Genus and Its Endophytes: A Review

Autor: Xiongming Luo, Xiaohong Chen, Lingli Zhang, Bin Liu, Lian Xie, Yan Ma, Min Zhang, Xiaobao Jin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Marine Drugs, Vol 22, Iss 4, p 158 (2024)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md22040158
Popis: The genus Bruguiera, a member of the Rhizophoraceae family, is predominantly found in coastal areas as a mangrove plant, boasting a rich and diverse community of endophytes. This review systematically compiled approximately 496 compounds derived from both the Bruguiera genus and its associated endophytes, including 152 terpenoids, 17 steroids, 16 sulfides, 44 alkaloids and peptides, 66 quinones, 68 polyketides, 19 flavonoids, 38 phenylpropanoids, 54 aromatic compounds, and 22 other compounds. Among these, 201 compounds exhibited a spectrum of activities, including cytotoxicity, antimicrobial, antioxidant, anti-inflammatory, antiviral, antidiabetic, insecticidal and mosquito repellent, and enzyme inhibitory properties, etc. These findings provided promising lead compounds for drug discovery. Certain similar or identical compounds were found to be simultaneously present in both Bruguiera plants and their endophytes, and the phenomenon of their interaction relationship was discussed.
Databáze: Directory of Open Access Journals