Generation of two isogenic iPSC lines from a healthy male donor of European ancestry

Autor: S. Edwards, L. Hagenau, B. Nowack, J. Rhode, M.F. Hossain, A. Tzvetkova, L.R. Jensen, A.W. Kuss
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Stem Cell Research, Vol 77, Iss , Pp 103403- (2024)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2024.103403
Popis: We have created two isogenic iPSC lines from fibroblasts of a healthy male donor of European ancestry. The cell lines express common pluripotency markers, are free of chromosomal aberrations and are able to differentiate into cells of all three germ layers. These iPSC are now a resource for genome editing with the aim of creating models of genetic disorders without having to depend on patient cells.
Databáze: Directory of Open Access Journals