The effect of the intensity of parasitic infection with Strongyloides papillosus and albendazole therapy on biochemical parameters in sheep blood
Autor: | Dimitrijević Blagoje, Borozan Sunčica, Jović S., Bacić D., Katić-Radivojević Sofija, Stojanović S., Savić Mila |
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Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Acta Veterinaria, Vol 63, Iss 5-6, Pp 581-600 (2013) |
Druh dokumentu: | article |
ISSN: | 0567-8315 1820-7448 |
DOI: | 10.2298/AVB1306581D |
Popis: | The aim of this report was to study the biochemical parameters in sheep blood under conditions of various intensities of parasitic infection with Strongyloides papillosus, as well as after therapy with albendazole (ABZ). Investigations were performed on sheep of the Würtemberg race (n = 30) in which were detected mild, moderate and high intensities of parasitic infection with S. papillosus. The control group (n = 10) was composed of sheep negative to parasitic infections. The degree and type of changes were monitored by determining the concentrations of glucose, total proteins, albumin, A/G ratio, AST, urea, total bilirubin, calcium, phosphorus, total LDH activity and isoenzymatic LDH1-5 distributions. On the basis of the obtained results, we determined, through isoenzymatic LDH distribution, that during parasitic infection with S. papillosus, there is ongoing damage to the liver, heart muscle and lung, while after therapy with ABZ, the liver suffers the most damage. The concentration of glucose, total proteins and albumin fell linearly with the rise in the intensity of parasitic infection (p0.05) and phosphorus (p |
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