Efficacy of application of Equisetum pyramidale Goldm. hydrogel for tissue restoration of induced skin lesions in Wistar rats

Autor: F. Carmignan, R. Matias, C. A. Carollo, D. M. Dourado, M. H. Fermiano, B. A. K. Silva, P. R. H. O. Bastos
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Brazilian Journal of Biology, Iss 0 (2019)
Druh dokumentu: article
ISSN: 1678-4375
1519-6984
DOI: 10.1590/1519-6984.184409
Popis: Abstract Medicinal plants, such as E. pyramidale, are alternatives against infections and assist in the healing process of wounds. We evaluated the effects of Hydrogel of E. pyramidale on the healing of cutaneous wounds in animal models by morphological, morphometric and histological analyses, and elucidated major components. The ethanolic extract of E. pyramidale shoots was submitted to phytochemical analysis. For cicatrizing activity assay, Wistar rats were used, and the groups evaluated were hydrogel containing ethanolic extract of E. pyramidale at 2% compared to control groups. The treatment periods were 3, 7 and 21 days, and macroscopic and microscopic analyses were performed. Data were submitted to Analysis of Variance (p
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