Association of low-dose glucocorticoid use and infection occurrence in systemic lupus erythematosus patients: a prospective cohort study

Autor: Kazuya Abe, Yuichi Ishikawa, Yasuhiko Kita, Nobuyuki Yajima, Eisuke Inoue, Ken-ei Sada, Yoshia Miyawaki, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 1478-6362
DOI: 10.1186/s13075-022-02869-9
Popis: Abstract Background Infection is a major cause of mortality in patients with systemic lupus erythematosus (SLE). Therefore, minimizing the risk of infection is an important clinical goal to improve the long-term prognosis of SLE patients. Treatment with ≥7.5 mg prednisolone (PSL) or equivalent has been reported to increase the risk of infections. However, it remains unclear whether
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