| Autor: |
Worrarak Norseeda, Guisheng Liu, Tawatchai Teltathum, Korawan Sringarm, Watcharapong Naraballobh, Trisadee Khamlor, Supamit Mekchay |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Veterinary Integrative Sciences, Vol 19, Iss 3, Pp 391-405 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2629-9968 |
| DOI: |
10.12982/VIS.2021.033 |
| Popis: |
Interleukin-17 receptor A (IL17RA) is one of the cytokine receptors of the pro-inflammatory interleukin-17 (IL17) cytokine family. The IL17 and IL17RA genes are involved in inflammatory and immune responses as well as reproductive process of mammals. The purposes of this study were to examine polymorphisms in the porcine IL17RA gene and to assess its effects on litter size traits in Large White and Landrace pigs. Three non-synonymous single nucleotide polymorphisms (SNPs) in the porcine IL17RA gene were verified. The porcine IL17RA c.785C>T (p.Ala262Val) was found to be segregating in the Large White and Landrace pigs. No polymorphisms in the coding region of the porcine IL17RA gene at the two non-synonymous SNPs loci of c.997G>A (p.Val333Ile) and c.1962T>G (p.Asp654Glu) were found. The porcine IL17RA c.785C>T polymorphism was significantly associated with the total number born (TNB) and the number born alive (NBA) in Large White pigs (PT was significantly associated with the TNB, NBA, total birth weight (TBW), and total weaning weight of piglets at 21 days (TWW) in Landrace pigs (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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