Long-Term Survival and PSA Control with Radiation and Immunotherapy for Node Positive Prostate Cancer

Autor:	M. Kamrava, Kwong Y. Tsang, R. A. Madan, A. Kaushal, C. N. Coleman, J. Gulley
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Immunologic diseases. Allergy RC581-607
Zdroj:	Clinical and Developmental Immunology, Vol 2009 (2009)
Druh dokumentu:	article
ISSN:	1740-2522 1740-2530
DOI:	10.1155/2009/363914
Popis:	We describe a patient with node positive prostate cancer treated with radiation, androgen deprivation, and immunotherapy with long-term overall survival and PSA control. ELISPOT immunoassay studies demonstrated PSA specific T-cells prior to starting vaccine therapy suggesting that this positive response may be related to an improved antitumor immune response of the patient, increased immunogenicity of the tumor, or decreased activation of immune escape pathways. Further evaluation of therapeutic cancer vaccines in combination with radiation and hormonal therapy in the definitive management of prostate cancer is warranted.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d411451655bd494da7bc6f26c7b6f20d Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF