Corneal Volume Measurements with Pentacam for Detection of Keratoconus and Subclinical Keratoconus

Autor: Nurullah Çağıl, Nagihan Uğurlu, Hasan Basri Çakmak, Sucattin İlker Kocamış, Hüseyin Simavlı, Şaban Şimşek
Jazyk: English<br />Turkish
Rok vydání: 2013
Předmět:
Zdroj: Türk Oftalmoloji Dergisi, Vol 43, Iss 2, Pp 77-82 (2013)
Druh dokumentu: article
ISSN: 1300-0659
2147-2661
DOI: 10.4274/tjo.43.97658
Popis: Pur po se: To estimate the sensitivity and specificity of corneal volume (CV) measurements in discriminating keratoconus and subclinical keratoconus from normal corneas. Ma te ri al and Met hod: Clinical records and Pentacam measurements of ninety-four patients with keratoconus, 36 patients with subclinical keratoconus, and 166 refractive surgery candidates with normal corneas were evaluated retrospectively. CV within 3, 5, 7, and 10 mm circles around the central cornea was measured in one eye of each patient, using the Pentacam. CV measurements in keratoconus and subclinical keratoconus were compared with normal corneas. Receiver operating characteristic (ROC) curves were used to determine the test’s overall predictive accuracy and to identify optimal CV cutoff points to maximize sensitivity and specificity in discriminating keratoconus and subclinical keratoconus from normal corneas. Re sults: Mean CV within a 3.0 mm circle around the central cornea was statistically lower in keratoconus (3.4±0.2 mm3, p
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