The potential benefit of stem cell therapy after stroke: an update
| Autor: | Banerjee S, Williamson DA, Habib N, Chataway J |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Vascular Health and Risk Management, Vol 2012, Iss default, Pp 569-580 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1176-6344 1178-2048 |
| Popis: | Soma Banerjee,1 Deborah A Williamson,2 Nagy Habib,3 Jeremy Chataway4,51Department of Stroke Medicine, Imperial College Healthcare NHS Trust, London, UK; 2Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand; 3Department of Surgery, Imperial College London, London, UK; 4Clinical Neurosciences, Imperial College Healthcare NHS Trust, London, UK; 5National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UKAbstract: Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.Keywords: stroke, stem cells, clinical trials |
| Databáze: | Directory of Open Access Journals |
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