Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of the HOST‐EXAM Trial

Autor: Jeehoon Kang, Sang‐Hyeon Park, Kyung Woo Park, Bon‐Kwon Koo, Huijin Lee, Minju Han, Doyeon Hwang, Han‐Mo Yang, In‐Ho Chae, Won‐Yong Shin, Ju Hyeon Oh, Yong Hoon Kim, Tae‐Ho Park, Bum Soo Kim, Jung‐Kyu Han, Eun‐Seok Shin, Hyo‐Soo Kim
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 18 (2024)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.124.035269
Popis: Background Clopidogrel monotherapy improved clinical outcomes compared with aspirin monotherapy during a chronic maintenance period in patients who underwent coronary stenting in the HOST‐EXAM (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Extended Antiplatelet Monotherapy) trial. However, it is uncertain whether the beneficial effect of clopidogrel over aspirin is different according to the renal function. Methods and Results We conducted a post hoc analysis of the HOST‐EXAM trial. Chronic kidney disease (CKD) was defined as baseline estimated glomerular filtration rate
Databáze: Directory of Open Access Journals