Popis: |
Objectives: This study aimed to identify alterations in pharmacokinetics in children on extracorporeal membrane oxygenation (ECMO), identify knowledge gaps, and inform future pharmacology studies.Data Sources: We systematically searched the databases MEDLINE, CINAHL, and Embase from earliest publication until November 2018 using a controlled vocabulary and keywords related to “ECMO” and “pharmacokinetics,” “pharmacology,” “drug disposition,” “dosing,” and “pediatrics.”Study Selection: Inclusion criteria were as follows: study population aged |