The clinical practice of ulcerative colitis in elderly patients: An investigation using a nationwide database in Japan

Autor: Rintaro Moroi, Hisashi Shiga, Kunio Tarasawa, Kota Yano, Yusuke Shimoyama, Masatake Kuroha, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori, Yoshitaka Kinouchi, Atsushi Masamune
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: JGH Open, Vol 5, Iss 8, Pp 842-848 (2021)
Druh dokumentu: article
ISSN: 2397-9070
DOI: 10.1002/jgh3.12541
Popis: Abstract Background and Aim The number of elderly patients with ulcerative colitis (UC) is increasing worldwide. The clinical practice of associated treatment is still unclear. Therefore, we aimed to analyze clinical treatment realities and mortality in elderly and non‐elderly patients with UC. Methods We collected UC patients' data using the diagnosis procedure combination (DPC) database system and divided eligible patients into elderly (≥65 years) and non‐elderly (≤64 years) groups. We investigated and compared their therapeutic histories (medical treatments vs. surgery). Logistic regression analysis was conducted to identify clinical factors affecting surgery and in‐hospital death in each group. Results The rates of systemic steroid injection, molecular targeting drug usage, and surgery were not different between the two age groups. Meanwhile, the rate of in‐hospital death in elderly patients was higher than that in non‐elderly patients (2.7% vs. 0.19%, P
Databáze: Directory of Open Access Journals