| Autor: |
Sandra M. Sacco, Wendy E. Ward |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Journal of Osteoporosis, Vol 2010 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
2042-0064 |
| DOI: |
10.4061/2010/708931 |
| Popis: |
The rapid decline in endogenous estrogen production that occurs during menopause is associated with significant bone loss and increased risk for fragility fracture. While hormone therapy (HT) is an effective means to re-establish endogenous estrogen levels and reduce the risk of future fracture, its use can be accompanied by undesirable side effects such as stroke and breast cancer. In this paper, we revisit the issue of whether HT can be both safe and effective for the prevention of postmenopausal bone loss by examining standard and alternative doses and formulations of HT. The aim of this paper is to continue the dialogue regarding the benefits and controversies of HT with the goal of encouraging the dissemination of-up-to date evidence that may influence how HT is viewed and prescribed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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