Glycemic variability: adverse clinical outcomes and how to improve it?

Autor:	Zheng Zhou, Bao Sun, Shiqiong Huang, Chunsheng Zhu, Meng Bian
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Glycemic variability Short-term glycemic variability Long-term glycemic variability Adverse clinical outcomes Beneficial measures Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-14 (2020)
Druh dokumentu:	article
ISSN:	1475-2840
DOI:	10.1186/s12933-020-01085-6
Popis:	Abstract Glycemic variability (GV), defined as an integral component of glucose homoeostasis, is emerging as an important metric to consider when assessing glycemic control in clinical practice. Although it remains yet no consensus, accumulating evidence has suggested that GV, representing either short-term (with-day and between-day variability) or long-term GV, was associated with an increased risk of diabetic macrovascular and microvascular complications, hypoglycemia, mortality rates and other adverse clinical outcomes. In this review, we summarize the adverse clinical outcomes of GV and discuss the beneficial measures, including continuous glucose monitoring, drugs, dietary interventions and exercise training, to improve it, aiming at better addressing the challenging aspect of blood glucose management.
Databáze:	Directory of Open Access Journals
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