Paradox of hypercholesterolaemia in highly trained, keto-adapted athletes

Autor: Brent C Creighton, Parker Neil Hyde, Carl M Maresh, William J Kraemer, Stephen D Phinney, Jeff S Volek
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMJ Open Sport & Exercise Medicine, Vol 4, Iss 1 (2018)
Druh dokumentu: article
ISSN: 2018-0004
2055-7647
DOI: 10.1136/bmjsem-2018-000429
Popis: Objective A growing number of ultra-endurance athletes have switched to a very low-carbohydrate/high-fat eating pattern. We compared markers of cholesterol and the lipoprotein profile in a group of elite ultra-runners consuming a high-carbohydrate (HC) or low-carbohydrate (LC) diet.Methods Fasting blood was obtained from competitive male ultra-endurance runners habitually consuming a very low-carbohydrate (LC; n=10) or high-carbohydrate (HC; n=10) diet to determine blood cholesterol profile, lipoprotein particle distribution and sterol biomarkers of cholesterol balance.Results Plasma total cholesterol, low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) cholesterol were all significantly greater (p
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