Genetic structure of the population and resistance to infections

Autor:	Sorin BUZINSCHI
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	genetic variability inflammatory response sensors factors that provide resistance to infections covid-19 immunity Medicine Medicine (General) R5-920
Zdroj:	Romanian Journal of Medical Practice, Vol 15, Iss 2, Pp 168-173 (2020)
Druh dokumentu:	article
ISSN:	1842-8258 2069-6108
DOI:	10.37897/RJMP.2020.2.8
Popis:	Numerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agents being considered consequences of the evolutionary pressure induced by the co-evolution of germs and population. The study presents examples related to these statements, the most notorious being the mutation of CCR5 delta-32 against HIV infection. Based on the genetic data, explanations are proposed regarding the very different evolution of people in the face of SARS-CoV-2 infection and the chances of an occult immunization of the population.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/408d91ad9f5b4d2688f546a6078fbe6a Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF