| Autor: |
Signe Abitz Winther, Miia Maininki Mannerla, Marie Frimodt-Møller, Frederik Persson, Tine Willum Hansen, Markku Lehto, Sohvi Hörkkö, Michael Blaut, Carol Forsblom, Per-Henrik Groop, Peter Rossing |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-94747-8 |
| Popis: |
Abstract Gastrointestinal dysbiosis is common among persons with type 1 diabetes (T1D), but its potential impact on diabetic nephropathy (DN) remains obscure. We examined whether faecal biomarkers, previously associated with low-grade gastrointestinal inflammation, differ between healthy controls and T1D subjects with and without DN. Faecal samples were analyzed for levels of calprotectin, intestinal alkaline phosphatase (IAP), short-chain fatty acids (SCFA) and immunoglobulins in subjects with T1D (n = 159) and healthy controls (NDC; n = 50). The subjects with T1D were stratified based on albuminuria: normoalbuminuria ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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