Comparison of C-reactive protein and high-sensitivity C-reactive protein levels in patients on hemodialysis

Autor: Imed Helal, Lilia Zerelli, Madiha Krid, Fethi ElYounsi, Hedi Ben Maiz, Bechir Zouari, Jaouida Adelmoula, Adel Kheder
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 23, Iss 3, Pp 477-483 (2012)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.95749
Popis: Chronic inflammation is highly prevalent in patients on hemodialysis (HD), as evidenced by increased levels of C-reactive protein (CRP). We compared CRP to high-sensitivity C-reactive protein (hs-CRP) to determine whether it has any clinical implications and prognostic significance in terms of mortality. CRP was measured using a standard immunoturbidometric assay on the COBAS; INTEGRA system and hs-CRP was measured using the Dade Behring on the Konelab Nephelometer in 50 patients on HD. CRP (≥6 mg/L) and hs-CRP (≥3 mg/L) levels were elevated in 30% and 54% of the patients, respectively. A significant correlation was noted between hs-CRP and CRP levels (r = 0.98, P
Databáze: Directory of Open Access Journals