| Autor: |
Jack Alderson, Darragh Herlihy, Aidan Hegarty, Paul Brennan, Sarah Power, Alan O'Hare, Matthew Crockett, Cindy Tong, Thibaut Galvain, Mesut Kocaman, Alexandra Ehm, John Thornton |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Stroke: Vascular and Interventional Neurology, Vol 2, Iss 6 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2694-5746 |
| DOI: |
10.1161/SVIN.121.000294 |
| Popis: |
Background Emerging evidence suggests that clinical and economic benefits of treatment with mechanical thrombectomy vary by level of reperfusion achieved, and the number of passes required to achieve revascularization. This study aimed to investigate the INFluence of revascularization Attempts on Clinical outcomes of mechanical Thrombectomy and the economic BURDEN (INFACT BURDEN) in Ireland using single center real‐world data from the Irish National Thrombectomy Service database. Methods Primary clinical outcomes were reperfusion (modified thrombolysis in cerebral infarction 2b‐3 or 2) among patients treated with 1–3 passes compared with ≥4 passes. Multivariable generalized linear models examined the association between number of passes with outcomes, with adjustment for covariates that may affect outcomes (eg, age, pre‐procedure modified Rankin Scale, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, occlusion site, time from symptom onset to groin puncture). A 90‐day decision‐tree and Markov model with a 5‐year time horizon evaluated the cost‐effectiveness of mechanical thrombectomy from the Irish public healthcare payer perspective. Results Eight hundred twenty three patients met the inclusion criteria. Compared with patients in the ≥4 passes group, patients in the 1–3 passes group achieved a significantly higher rate of successful reperfusion (94% versus 78%, odds ratio [OR], 4.7; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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