Emerging role of miRNAs, lncRNAs, and circRNAs in pregnancy-associated diseases
| Autor: | Xiaoxiao Fu, Yuling Li, Zhen Zhang, Bin Wang, Ran Wei, Chu Chu, Ke Xu, Lihua Li, Yonglin Liu, Xia Li, Yanjie Yin |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Chinese Medical Journal, Vol 136, Iss 11, Pp 1300-1310 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0366-6999 2542-5641 00000000 |
| DOI: | 10.1097/CM9.0000000000002595 |
| Popis: | Abstract. Accumulating studies have demonstrated that non-coding RNAs (ncRNAs), functioning as important regulators of transcription and translation, are involved in the establishment and maintenance of pregnancy, especially the maternal immune adaptation process. The endometrial stromal cells (ESCs), trophoblast cells, and decidua immune cells that reside at the maternal–fetal interface are thought to play significant roles in normal pregnancy and pregnancy-associated diseases. Here, we reviewed the up-to-date evidence on how microRNA, long non-coding RNA, and circular RNA regulate ESCs, trophoblast cells, and immune cells and discussed the potential applications of these ncRNAs as diagnostic and therapeutic markers in pregnancy complications. |
| Databáze: | Directory of Open Access Journals |
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