Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

Autor:	Giuseppina Autore, Stefania Marzocco, Carmen Formisano, Maurizio Bruno, Sergio Rosselli, Mariem Ben Jemia, Felice Senatore
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Magydaris tomentosa coumarins furanocoumarins xanthotoxin xanthotoxol isopimpinellin osthole bergaptene MCF-7 Organic chemistry QD241-441
Zdroj:	Molecules, Vol 20, Iss 1, Pp 1571-1578 (2015)
Druh dokumentu:	article
ISSN:	1420-3049 20011571
DOI:	10.3390/molecules20011571
Popis:	The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene. Other coumarins such as 7-methoxy-8-(2-formyl-2-methylpropyl) coumarin and osthole also occurred. The antiproliferative activity of Magydaris tomentosa flower extract has been evaluated in vitro on murine monocye/macrophages (J774A.1), human melanoma (A375) and human breast cancer (MCF-7) tumor cell lines, showing a major activity against the latter.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e403640350444050a8b7412476b6c2e8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF