MRI Based Preterm White Matter Injury Classification: The Importance of Sequential Imaging in Determining Severity of Injury.

Autor: Miriam Martinez-Biarge, Floris Groenendaal, Karina J Kersbergen, Manon J N L Benders, Francesca Foti, Frances M Cowan, Linda S de Vries
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: PLoS ONE, Vol 11, Iss 6, p e0156245 (2016)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0156245
Popis: BACKGROUND:The evolution of non-hemorrhagic white matter injury (WMI) based on sequential magnetic resonance imaging (MRI) has not been well studied. Our aim was to describe sequential MRI findings in preterm infants with non-hemorrhagic WMI and to develop an MRI classification system for preterm WMI based on these findings. METHODS:Eighty-two preterm infants (gestation ≤35 weeks) were retrospectively included. WMI was diagnosed and classified based on sequential cranial ultrasound (cUS) and confirmed on MRI. RESULTS:138 MRIs were obtained at three time-points: early (
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