Intact fibroblast growth factor 23 in heart failure with reduced and mildly reduced ejection fraction

Autor:	Giuseppe Vergaro, Annamaria Del Franco, Alberto Aimo, Francesco Gentile, Vincenzo Castiglione, Federica Saponaro, Silvia Masotti, Concetta Prontera, Niccolò Fusari, Michele Emdin, Claudio Passino
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Fibroblast growth factor Heart failure Calcium-phosphate metabolism Prognosis Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-8 (2023)
Druh dokumentu:	article
ISSN:	1471-2261
DOI:	10.1186/s12872-023-03441-2
Popis:	Abstract Background Fibroblast growth factor-23 (FGF23) has been associated to left ventricular (LV) hypertrophy and heart failure (HF) severity. We aimed to investigate the clinical correlates and prognostic value of intact FGF23 (iFGF23) in HF patients. Methods Patients with stable HF and left ventricular ejection fraction (LVEF) 50.9 pg/mL. LVEF decreased from the first iFGF23 tertile to the third tertile (p = 0.014). N-terminal pro-B-type natriuretic peptide (NT-proBNP) increased from the first to the third tertile (p = 0.001), while peak oxygen consumption decreased (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/4007a28442bc4dbf84d7df535a3321b2 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ