The role of interleukin-1ß and interleukin-33 in atopic dermatitis

Autor: Rania M. Abdel Hay, Noha F. Ibrahim, Dina Metwally, Laila A. Rashed
Jazyk: English<br />Spanish; Castilian<br />French<br />Polish
Rok vydání: 2013
Předmět:
Zdroj: Nasza Dermatologia Online, Vol 4, Iss 1, Pp 11-14 (2013)
Druh dokumentu: article
ISSN: 2081-9390
Popis: Introduction: Interleukin-1 super family is a group of cytokines that play a role in the regulation of immune and inflammatory responses. Interleukin-33 is a member of this family and is known to induce expression of the T helper2 cytokines that are important players in atopic dermatitis. Aim: To evaluate the expression of interleukins-1ß and 33 as T helper2 cytokines inducers in patients with atopic dermatitis. Materials andMethods: This study included 20 atopic patients and 20 apparently healthy individuals serving as controls. Skin biopsies from all participants will be examined for detection of interleukins-1ß and 33 by ELISA technique.Results: Both interleukins were statistically higher (P
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